[Windows] Portal Web Design

Hi there,

Maybe this is not the right place, but my questions are somehow relevant to web design on Windows. I am a newbie to web design and going to design a portal web page similar to the following link:
http://www.eh3.uc.edu:8080/GenomicsPortals/

It looks that the above portal was designed on Unix/Linux using JavaScript and Microsoft FrontPage 5.0 processing datasets in MySQL database. As I only have MS Visual Studio 2008 Prof, I want to go with ASP.NET and ADO.NET to do it. Does anybody know if this will work? Can the portal web pages designed based on Windows .NET framework be browsed without any problem on Linux/Unix. i.e., other platforms than the Windows? Regardless, any suggestions on how to start design such a portal web page (books, online resources, framework and tools) would be highly appreciated. Thank you in advance.

Robert
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